Tissue transglutaminase IgG
- Test Name:
- Tissue transglutaminase IgG
- Synonyms:
-
TTG IgG
-
Ordering Information:
-
Laboratory staff:
• If "TTG" is written alone, order "Tissue transglutaminase IgA" (ATTG; TTG IgA; Celiac screen)
• Tissue transglutaminase IgG should only be ordered if the requisition clearly states TTG IgG. - Collection Device/Tube Type:
-
3.5 mL blood - GOLD SST (gel)
- Submission Requirements:
- 1 mL serum
- Frequency of Testing:
-
Monday - Friday
- Reference Range:
- < 15 kIU/L (negative)
- Comments:
-
Physician Information:
• Initiating a gluten-free diet prior to referral or prior to screening will interfere with the diagnostic test for celiac diseases.
• Please note that individuals may exhibit a wide range of responses to gluten challenge over varying periods of time. Some patients only require a diet containing gluten (minimum 3 g/day gluten or approximately 1-2 slices of bread/day) for at least 2 weeks to exhibit histological changes and at least 4 weeks for tTG IgA levels to increase. Others may require a challenge for as long as two years prior to development of intestinal injury or antibody response. Celiac disease serology during the challenge should be repeated every 4-6 months or immediately with the development of symptoms. - Last Reviewed:
- 04 May 2023
